| 摘要 |
PROBLEM TO BE SOLVED: To provide inhibitors of poly(ADP-ribose)polymerase (PARP), methods of producing the inhibitors, and methods of treating patients using the inhibitors.SOLUTION: The invention provides compounds represented by formula (IV). (One of R1A and R1B is H, and the other is R1, OR1, SR1, S(O)R1, SO2R1, NH2, NHR1, N(R1)2, C(O)R1, C(O)NH2, C(O)NHR1, C(O)N(R1)2, NHC(O)R1, NR1C(O)R1, NHSO2R1, NR1SO2R1, NHC(O)OR1, NR1C(O)OR1, SO2NH2, SO2NHR1, SO2N(R1)2, NHC(O)NH2, NHC(O)NHR1, NHC(O)N(R1)2, OH, C(O)OH, CN, CF3, OCF3, CF2CF3 or halogen.)SELECTED DRAWING: None |
