发明名称 |
ANTIGEN BINDING COMPLEX HAVING AGONISTIC ACTIVITY AND METHODS OF USE |
摘要 |
Provided herein are antigen binding polypeptides and complexes thereof having agonist activity. Also provided are methods for screening for complexes or polypeptides having agonist activity, enhancing the agonist activity of a polypeptide, and for agonizing a cell surface receptor using the complexes and polypeptide described herein. |
申请公布号 |
WO2016164480(A1) |
申请公布日期 |
2016.10.13 |
申请号 |
WO2016US26245 |
申请日期 |
2016.04.06 |
申请人 |
GENENTECH, INC.;F. HOFFMANN-LA ROCHE AG |
发明人 |
LAZAR, Greg;KIM, Jeong;ZHU, Jing;YANG, Yanli;BREZSKI, Randall |
分类号 |
C07K16/28;A61K39/00;C07K16/32 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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