| 发明名称 |
MORPHINAN DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN |
| 摘要 |
The present invention relates to compounds and their use as ligands for mu opioid receptors. Also included are methods for preparing the compounds and pharmaceutical compositions containing the compounds. In one or more embodiments of the invention, a compound according to Formula I is provided: and pharmaceutically acceptable salts thereof, wherein R1-R11 are as described herein. |
| 申请公布号 |
WO2016182840(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
WO2016US30933 |
申请日期 |
2016.05.05 |
| 申请人 |
NEKTAR THERAPEUTICS |
发明人 |
ANAND, Neel;AURRECOECHEA, Natalia;CHENG, Lin;DENG, Bo-liang;O'MAHONY, Donogh;MU, Yongqi;KROGH-JESPERSEN, Erik |
| 分类号 |
C07D221/28;A61K31/439;A61P25/04;C07D401/12;C07D407/12;C07D417/12;C07D513/08 |
主分类号 |
C07D221/28 |
| 代理机构 |
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