发明名称 PIPERIDINDERIVATER
摘要 The invention relates to compounds of formula where hetaryl I, hetaryl II, R1, R2, R3, R4, m, n, and o are as defined in the specification or to pharmaceutically active acid addition salts thereof. The compounds of formula I are modulators for amyloid beta and thus may be useful for the treatment or prevention of a disease associated with the deposition of beta-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
申请公布号 DK2536710(T3) 申请公布日期 2016.08.22
申请号 DK20110702848T 申请日期 2011.02.14
申请人 F.HOFFMANN-LA ROCHE AG 发明人 BAUMANN, Karlheinz;FLOHR, Alexander;GOETSCHI, Erwin;GREEN, Luke;JOLIDON, Synese;KNUST, Henner;LIMBERG, Anja;LUEBBERS, Thomas;THOMAS, Andrew
分类号 C07D401/14;A61K31/4523;A61P25/28;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D498/04 主分类号 C07D401/14
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