Pre-Filter Fragmentation

摘要

A method of fragmenting ions is disclosed comprising providing a linear ion trap comprising: (i) a first electrode set comprising a plurality of first electrodes; (ii) a second electrode set arranged downstream of the first electrode set and comprising a plurality of second electrodes; and (iii) a third electrode set arranged downstream of the second electrode set and comprising a plurality of third electrodes. Ions are axially confined within the linear ion trap. Either: (i) a potential difference between at least some of the first electrodes and at least some of the second electrodes; and/or (ii) a potential difference between at least some of the second electrodes and at least some of the third electrodes, is varied in order to accelerate at least some ions confined within the linear ion trap in order to cause the ions to fragment so as to form fragment or daughter ions.

主权项

1. A method of fragmenting ions comprising:
providing a linear ion trap comprising: (i) a first electrode set comprising a plurality of first electrodes; (ii) a second electrode set arranged downstream of said first electrode set and comprising a plurality of second electrodes; and (iii) a third electrode set arranged downstream of said second electrode set and comprising a plurality of third electrodes; axially confining ions within said linear ion trap; and varying either: (i) a potential difference between at least some of said first electrodes and at least some of said second electrodes; and/or (ii) a potential difference between at least some of said second electrodes and at least some of said third electrodes, in order to accelerate at least some ions confined within said linear ion trap in order to cause said ions to fragment so as to form fragment or daughter ions.