| 发明名称 | Preparation method for optically active bicyclic gamma-amino acid compound | ||
| 摘要 | An object of the present invention is to provide an optically active bicyclic γ-amino acid derivative in a high purity. The object can be attained by a mixture of compounds represented by the general formulas (I) and (I′), or a method for producing a compound represented by the general formula (VII) or a salt thereof via the compound (I):; wherein R1 and R2 each represent a C1-6 alkyl group or the like; and R3 represents a cyano group or the like, ; | ||
| 申请公布号 | US9469623(B2) | 申请公布日期 | 2016.10.18 |
| 申请号 | US201514615972 | 申请日期 | 2015.02.06 |
| 申请人 | Daiichi Sankyo Company, Limited | 发明人 | Nakamura Yoshitaka;Ukai Kazutoshi;Kitawaki Takafumi;Nakajima Takumi;Kitagawa Yutaka;Furuya Yukito;Imai Makoto;Numagami Eiji;Wakayama Masakazu;Saito Ayako |
| 分类号 | C07C67/343;C07C211/27;C07C201/16;C07C253/34;C07C253/30;C07C227/42;C07C253/10;C07D319/06;C07C255/47;C07C201/12;C07C205/50;C07C229/32;C07C227/04;C07C67/00;C07C69/608;C07C253/00 | 主分类号 | C07C67/343 |
| 代理机构 | Dorsey & Whitney LLP | 代理人 | Dorsey & Whitney LLP |
| 主权项 | 1. A mixture of compounds of formulas (I) and (I′): wherein R1 and R2 are each independently selected from a hydrogen atom and a C1-6 alkyl group, or R1 and R2 are bonded to each other to form an isopropylidene group; and R3 is a cyano group or a nitromethyl group. | ||
| 地址 | Tokyo JP | ||