发明名称 |
Method for detecting carcinomas in a solubilized cervical body sample |
摘要 |
<p>The present invention relates to a method for the early diagnosis of carcinomas and their preliminary stages, which comprises determining the overexpression of a cell cycle regulatory protein in a solubilized body sample. The present invention is particularly directed to a method for detecting cervical carcinomas, cervical intraepithelial neoplasias, or cervical carcinomas in-situ from a solubilized cervical body sample of a human subject, by solubilizing the cervical body sample in a lysis buffer, and determining the overexpression of cyclin dependent kinase inhibitor p16 in the solubilized cervical sample. The invention also concerns a test kit usable for this purpose as well as an in-vitro diagnostic device.</p> |
申请公布号 |
EP1507148(B1) |
申请公布日期 |
2005.02.23 |
申请号 |
EP20030103218 |
申请日期 |
2003.08.25 |
申请人 |
MTM LABORATORIES AG |
发明人 |
RIDDER, RUEDIGER, DR.;REICHERT, ANJA DR.;HERKERT, MATTHIAS DR.;VON KNEBEL DOEBERITZ, MAGNUS DR. |
分类号 |
G01N33/574;(IPC1-7):G01N33/574 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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