发明名称 Crystalline form of calcium (3S)-tetrahydro-3-furanyl-(1S,2R)-3- [[(4-aminophenyl)sulfonyl]-(isobutyl)-amino]-1-benzyl-2- (phosphonooxy)propylcarbamate, process for its preparation, pharmaceutical composition comprising it and its use
摘要 <p>The invention relates to a crystalline form of calcium (3S)-tetrahydro-3-furanyl-(1S,2R)-3-[[(4-aminophenyl)sulfonyl]- (isobutyl)-amino]-1-benzyl-2-(phosphonooxy)propylcarbamate of formula (I), to a process for its preparation, to its use for medical purposes, and to a pharmaceutical composition comprising it. Calcium (3S)-tetrahydro-3-furanyl-(1S,2R)-3-[[(4- aminophenyl)sulfonyl]-(isobutyl)-amino]-1-benzyl-2- (phosphonooxy)propylcarbamate of formula (I) is a compound with antiviral activity and is useful for the treatment of diseases caused by retroviruses, such as HIV infections, AIDS, hepatitis B and hepatitis C, and related diseases.</p>
申请公布号 SK285311(B6) 申请公布日期 2006.10.05
申请号 SK20010000076 申请日期 1999.07.15
申请人 GLAXO GROUP LIMITED 发明人 ARMITAGE IAN GORDON;SEARLE ANDREW DAVID;SINGH HARDEV
分类号 A61K31/665;A61K38/55;A61P31/12;A61P31/14;A61P31/18;A61P37/04;C07F9/655 主分类号 A61K31/665
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