发明名称 |
Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
摘要 |
Partially desulphated glycosaminoglycan derivatives are described, particularly heparin, and more particularly a compound of formula (I) where the U, R and R<SUB>1 </SUB>groups have the meanings indicated in the description. These glycosaminoglycan derivatives have antiangiogenic and heparanase-inhibiting activity and are devoid of anticoagulant activity.
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申请公布号 |
US2008051567(A1) |
申请公布日期 |
2008.02.28 |
申请号 |
US20070882978 |
申请日期 |
2007.08.08 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHERIUNITE S.P.A. |
发明人 |
CASU BENITO;TORRI GIANGIACOMO;NAGGI ANNA M.;GIANNINI GIUSEPPE;PISANO CLAUDIO;PENCO SERGIO |
分类号 |
C08B37/10;C07H5/04 |
主分类号 |
C08B37/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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