发明名称 PRAZOLE DERIVATIVES AND SALTS THEREOF AND USE OF SAME
摘要 The present invention relates to derivatives of compounds (formula (I) or (II)) and their salts, wherein R<SUB>1 </SUB>represents lower alkyl or the lower alkyl substituted by halogen atoms, R<SUB>2 </SUB>represents straight-chain or branched-chain alkyl containing 1-4 carbon atoms and R<SUB>3 </SUB>represents hydrogen atom or alkali metals such as lithium, sodium, potassium or alkaline-earth metals such as magnesium and calcium. In the present invention, compounds with formula (I) or (II) and their derivatives or salts thereof acceptable in pharmacy and pharmacology can remarkably improve the effectiveness of anti-ulcer in alimentary tract, weakly inhibit gastric acid secretion, reduce the risk of stomach cancer and have excellent bio-availability and other in-vive pharmacokinetic characteristics.
申请公布号 US2008070942(A1) 申请公布日期 2008.03.20
申请号 US20050576425 申请日期 2005.09.23
申请人 JIANGSU HANSEN PHARMACEUTICAL CO., LTD. 发明人 ZHONG HUIJUAN;LV AIFENG
分类号 A61K31/4745;A61K31/4439;C07D403/02;C07D471/02 主分类号 A61K31/4745
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