发明名称 NON-HYGROSCOPIC SALTS OF 3-(2,2,2-TRIMETHYLHYDRAZINUM)PROPIONATE,A METHOD OF PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THEREOF
摘要 New salts of 3-(2,2,2-trimethylhydrazinium)propionate as well as method for manufacture and pharmaceutical compositions on their basis are described. The common formulae of the compound is X-(CH3)3N+NHCH2CH2COOH where X- is an acid anion chosen from group of pharmaceutically acceptable acids. Particularly preferable for manufacture of various medicinal formulations are substantially non-hygroscopic acid salts of fumaric acid, phosphoric acid, orotic acid, oxalic acid, maleic acid, pamoic acid as well as 3-(2,2,2-trimethylhydrazinium)propionate orotate and galactarate. All pharmaceutical formulations can be administered orally, parenterally, subcutaneously, transdermally and rectally.
申请公布号 LV13279(B) 申请公布日期 2005.11.20
申请号 LV20030000087 申请日期 2003.08.04
申请人 GRINDEKS, PUBLISKA A/S 发明人 KALVINS,IVARS;BIRMANS,ANATOLIJS
分类号 A61K31/205;(IPC1-7):A61K31/205 主分类号 A61K31/205
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