Nichtresorbierbares Zweiphasen-Hornhautimplantat und Verfahren zu seiner Herstellung

摘要

The present invention provides a non-biodegradable corneal implant comprising (1) a polymerized transparent collagenous core having acylated amine or esterified carboxyl groups, and (2) a polymerized periphery surrounding the core, the periphery comprising fibrous collagen, e.g., Type I, being in the form of fibrils under suitable physiological conditions, or fibrillar collagenous material prepared from intact tissue. A method of preparing such an implant is also provided.