发明名称 Purification process of particles similar human papillomavirus
摘要 <p>A process for purifying papillomavirus virus-like particles (VLPs) includes the step of passing a partially purified VLP-containing solution through a hydroxyapatite chromatography column. The VLPs are then eluted using a buffer containing phosphate anion. The advantages of this method include the recovery of a high yield of intact VLPs.</p>
申请公布号 CZ20010570(A3) 申请公布日期 2001.09.12
申请号 CZ20010000570 申请日期 1999.08.10
申请人 MERCK & CO., INC. 发明人 COOK JAMES C. III.
分类号 C12N15/09;A61K39/12;A61P35/00;C07K1/16;C07K14/025;C12N7/02;C12N7/04;C12P21/00;C12R1/865;(IPC1-7):C12N7/02 主分类号 C12N15/09
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