| 摘要 |
The present invention provides an animal for drug efficacy evaluation produced by administering an aqueous solution, in which cigarette smoke is dissolved in water or physiological saline, directly to a lower airway of an animal except a human so as to develop chronic obstructive pulmonary disease; a method for developing chronic obstructive pulmonary disease in an animal for drug efficacy evaluation including administering an aqueous solution, in which cigarette smoke is dissolved in water or physiological saline, directly to a lower airway of an animal except a human; and a method for evaluating drug efficacy including administering a drug to the animal for drug efficacy evaluation and then evaluating the effect of the drug.
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