发明名称 |
COMPOSITIONS FOR THE TREATMENT OF NEOPLASTIC DISEASES |
摘要 |
Pharmaceutical compositions and methods for the treatment of neoplastic disease and comprising the combination of a taxane, such as docetaxel, with a CYP3A4 inhibitor, such as ritonavir. Methods of treatment of neoplastic disease incorporating the administration of a taxane and the administration of a CYP3A4 inhibitor, either simultaneously or separately, are also included. Further, kits for carrying out the methods are included. Solid pharmaceutical taxane compositions for oral administration comprising a substantially amorphous taxane, a carrier and a surfactant are also included.
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申请公布号 |
CA2696622(A1) |
申请公布日期 |
2009.03.05 |
申请号 |
CA20082696622 |
申请日期 |
2008.08.22 |
申请人 |
STICHTING HET NEDERLANDS KANKER INSTITUUT;SLOTERVAART PARTICIPATIES BV |
发明人 |
BEIJNEN, JACOB HENDRIK;SCHELLENS, JOHANNES HENRICUS MATTHIAS;MOES, JOHANNES;NUIJEN, BASTIAAN |
分类号 |
A61K9/14;A61K9/19;A61K9/48;A61K31/337;A61K31/426;A61K45/06;A61P35/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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