发明名称 |
Use of a halogenated 2-phenyl-1,2-ethanediol dicarbamate enantiomer or enantiomeric mixture wherein one enantiomer predominates for preventing or treating bipolar disorder |
摘要 |
Described is the use of a medicament for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of formula (I) or enantiomeric mixture wherein one enantiomer of formula (I) predominates wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
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申请公布号 |
NZ527989(A) |
申请公布日期 |
2005.12.23 |
申请号 |
NZ20020527989 |
申请日期 |
2002.02.21 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC |
发明人 |
PLATA-SALAMAN, CARLOS R;ZHAO, BOYU;TWYMAN, ROY E;CHOI, YONG MOON;GORDON, ROBERT |
分类号 |
A61P25/00;A61K31/27;A61P25/20;A61P25/24;(IPC1-7):A61K31/27 |
主分类号 |
A61P25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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