发明名称 Use of a halogenated 2-phenyl-1,2-ethanediol dicarbamate enantiomer or enantiomeric mixture wherein one enantiomer predominates for preventing or treating bipolar disorder
摘要 Described is the use of a medicament for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of formula (I) or enantiomeric mixture wherein one enantiomer of formula (I) predominates wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
申请公布号 NZ527989(A) 申请公布日期 2005.12.23
申请号 NZ20020527989 申请日期 2002.02.21
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC 发明人 PLATA-SALAMAN, CARLOS R;ZHAO, BOYU;TWYMAN, ROY E;CHOI, YONG MOON;GORDON, ROBERT
分类号 A61P25/00;A61K31/27;A61P25/20;A61P25/24;(IPC1-7):A61K31/27 主分类号 A61P25/00
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