INFLAMMATION-TRANSITION-SUPPRESSING SKIN TOPICAL COMPOSITION

摘要

The present invention addresses the problem of suppressing the transition to inflammation (redness, warmth, swelling, pain) by controlling the activation of epithelial cells attributable to DAMPs. The inventors screened active ingredients for suppressing NO production and IL-8 gene expression of epithelial cells activated by DAMPs stimulation, resulting in the discovery of suppressive effects in perilla extract and scutellaria extract. Provided is an inflammation-transition-suppressing skin topical composition or the like having these extracts as active ingredients.