| 发明名称 | Methods and compositions for targeting cancer stem cells | ||
| 摘要 | The present invention relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present invention provides compounds as therapeutic agents against cancer stem cells. | ||
| 申请公布号 | US9468632(B2) | 申请公布日期 | 2016.10.18 |
| 申请号 | US201314647770 | 申请日期 | 2013.11.26 |
| 申请人 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 发明人 | Buckanovich Ronald;Larsen Scott D.;Yang Kun |
| 分类号 | A61K31/404;A61K31/4439;A61K45/06;A61K31/337;A61K31/555;A61K33/24;C07D401/04;C07D471/04;C07D209/04;G01N33/574;A61K31/136;A61K31/4035;A61K31/437 | 主分类号 | A61K31/404 |
| 代理机构 | Casimir Jones, S.C. | 代理人 | Casimir Jones, S.C. ;Casimir David;Arenson Tanya |
| 主权项 | 1. A method of treating ovarian cancer, comprising: administering a compound having the structure wherein R3-R6 are independently selected from the group consisting of a halogen, H, an alkyl, a cycloalkyl, an aryl, an alkenyl, a cycloalkyl, alkynl, and a substituted version of the aforementioned groups to a subject diagnosed with ovarian cancer under conditions such that said compound kills or inhibits the growth of said ovarian cancer. | ||
| 地址 | Ann Arbor MI US | ||