发明名称 NOVEL USE OF BIOTIN AND NATURAL ESSENTIAL OILS FOR BOVINE ANIMALS FOR THE PREVENTION AND TREATMENT OF KETOSIS
摘要 The present invention is made for the prevention of ketosis or minimizing the effects of ketosis in ruminant animals. This purpose is achieved by feeding to the animal biotin in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol. The present invention is useful because it is capable of preventing and/or inhibiting ketosis of calving ruminant animals and the subsequent need for veterinary treatment. In a preferred embodiment of a feeding concept for dairy cattle, especially calving dairy cattle, biotin being used in an amount sufficient to provide a daily dosage of 10 mg to 20 mg per head to which it is to be administered. It is at present contemplated that the essential oils are administered in amounts (total dosage ranges of essential oils) of 1 to 1.5 g per head per day.
申请公布号 US2016317500(A1) 申请公布日期 2016.11.03
申请号 US201415102316 申请日期 2014.12.11
申请人 DSM IP ASSETS B.V. 发明人 IMMIG Irmgard;STEINBERG Wolfgang;MC GRATH Joseph
分类号 A61K31/4188;A61K31/085;A23K20/174;A23K50/10;A23K20/158;A61K31/05;A61K31/11 主分类号 A61K31/4188
代理机构 代理人
主权项 1. A method for the prevention of ketosis or minimizing the effects of ketosis in ruminant animals characterized by administering to the animal biotin in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol.
地址 Heerlen NL