发明名称 |
METHOD OF TREATING OR PREVENTING PAIN |
摘要 |
Compounds for use in the treatment or prophylaxis of pain, including acute and chronic pain (e.g., nociceptive pain, neuropathic pain, headaches, migraine), represented by general formula I:;in which:the dotted line represents a single or a double bond; and R5 and R5′ are independently —H, —OH or —OR6, where R6 is a linear or branched C1-C4 alkyl; X is —CH2O—; Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; m is 1; and n is an integer of 1-5. The compounds of the invention are also effective for reducing inflammation and may be used alone or in combination with other analgesics. |
申请公布号 |
US2016317479(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201615143707 |
申请日期 |
2016.05.02 |
申请人 |
Novaremed Ltd. |
发明人 |
Kaplan Eliahu |
分类号 |
A61K31/165;A61K9/00 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating or preventing pain in a human or non-human animal patient in need thereof, which method comprises administering to said patient a therapeutically effective amount of at least one compound represented by formula I: wherein: represents a single or a double bond; R5 and R5′ are independently —H, —OH or —OR6, wherein R6 is a linear or branched C1-C4 alkyl; X is —CH2O—; Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; m is 1; and n is an integer of 1, 2, 3, 4, or 5; or a pharmaceutically acceptable salt, prodrug, metabolite, or hydrate thereof. |
地址 |
Petah Tiqwa IL |