发明名称 |
COMBINATION THERAPY WITH MDM2 AND EGFR INHIBITORS |
摘要 |
Provided is a method of treating a proliferative disease, condition, or disorder in a subject by administering a combination of an inhibitor of p53 and MDM2 binding and an EGFR inhibitor. Various embodiments of the disclosed methods provide a synergistic anti-proliferative or anti-apoptotic effect compared to administration of one agent alone. |
申请公布号 |
CA2805658(C) |
申请公布日期 |
2016.12.13 |
申请号 |
CA20112805658 |
申请日期 |
2011.07.21 |
申请人 |
ERRICO, JOSEPH P. |
发明人 |
ERRICO, JOSEPH P.;MUGRAGE, BENJAMIN;TURCHI, IGNATIUS;SILLS, MATTHEW;ONG, JANE;ALLOCCO, JOHN;WINES, PAM;BASTOS, MARGARITA |
分类号 |
A61K31/517;A61P35/00;G01N33/48 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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