发明名称 AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLPROTEASES
摘要 The present invention provides a compound of Formula (I) or Formula (II): enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
申请公布号 KR20060008918(A) 申请公布日期 2006.01.27
申请号 KR20057020165 申请日期 2004.04.23
申请人 INCYTE COPORATION 发明人 YAO WENQING;ZHOU JINCONG;XU MEIZHONG;ZHANG FENGLEI;METCALF BRIAN
分类号 C07D491/10;A61K;A61K31/4188;A61K31/424;A61K31/428;A61K31/4747;C07D;C07D471/10;C07D497/10 主分类号 C07D491/10
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