发明名称 |
GLUCOSE-SENSITIVE CELL PROTECTING AGENT |
摘要 |
Provided is a means for reducing adverse effects of a high glucose concentration on the living body. Provided are: a preparation for protecting glucose-sensitive cells from glucose toxicity caused by a high glucose concentration, the preparation containing N-acetyl-D-mannosamine; a pharmaceutical composition for protecting glucose-sensitive cells from glucose toxicity caused by a high glucose concentration, the pharmaceutical composition containing an effective amount of N-acetyl-D-mannosamine and a pharmaceutically acceptable carrier; a use of N-acetyl-D-mannosamine to prepare a drug for protecting glucose-sensitive cells from glucose toxicity caused by a high glucose concentration; and a method for protecting glucose-sensitive cells from glucose toxicity caused by a high glucose concentration, the method including a step for administering an effective amount of N-acetyl-D-mannosamine to a subject in need thereof. The glucose-sensitive cells are selected from the group consisting of nerve cells, renal cells, and vascular endothelial cells. |
申请公布号 |
WO2016159335(A1) |
申请公布日期 |
2016.10.06 |
申请号 |
WO2016JP60882 |
申请日期 |
2016.04.01 |
申请人 |
THE UNIVERSITY OF TOKYO |
发明人 |
SHIOTA, Kunio;HAYAKAWA, Koji;TAKAMORI, Mitsuko;FUJII, Ryosuke;ITO, Yukishige |
分类号 |
A61K31/7008;A61P3/10;A61P25/00;A61P43/00 |
主分类号 |
A61K31/7008 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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