PTH-receptor og screeningsassay der anvender denne

摘要

The invention provides a novel PTH receptor polypeptide, r´Nt, characterised by a deletion of the extracellular amino-terminus, ligand binding domain of the receptor. Additionally disclosed are nucleic acid molecules encoding the receptor. The receptor has a minimal domain for ligand binding and is useful in screening assays designated for the identification of agonists and antagonists of PTH receptor activity.