THIOPHENE COMPOUND.

摘要

A thiophene compound represented by general formula (I), a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising this compound and pharmaceutical additives, and an antipsychotic containing this compound as the active ingredient; wherein each symbol is as defined in the specification. This compound has pharmacological activities necessary for an antipsychotic, such as, inhibition of active exercise, antiapomorphine activity, methaphetamine antogonism, and potentiation of tetrabenazine-induced blepharoptosis. It is also useful as an antipsychotic which is reduced in the side effect against an extrapyramidal system and as a non-benzodiazepine ataractic.