AMPHIPHILIC MACROCYCLIC DERIVATIVES AND THEIR ANALOGUES
摘要
Soluble amphiphilic macrocycle analogues having lipophilic groups attached to one side of the units making up the macrocycle and hydrophilic groups attached to the other side. These amphiphilic macrocyclic derivatives have the ability to self-assemble in aqueous solvent forming micelles or vesicles and can be used as hosts for the solubilisation and/or stabilisation of various compounds. Embodiments of the present invention utilise macrocyclic oligosaccharides and preferably cyclodextrin as the macrocyclic derivatives to be modified.
申请公布号
WO0183564(A1)
申请公布日期
2001.11.08
申请号
WO2001IE00057
申请日期
2001.04.30
申请人
UNIVERSITY COLLEGE DUBLIN;DARCY, RAPHAEL;PENKLER, LAWRENCE, JOHN;RAVOO, BART, JAN
发明人
DARCY, RAPHAEL;PENKLER, LAWRENCE, JOHN;RAVOO, BART, JAN