Methods of editing target nucleic acids are provided using a guide RNA and a Cas9 protein to excise exons in a target gene and where the edited gene is expressed to produce a truncated polypeptide.
申请公布号
WO2016089866(A1)
申请公布日期
2016.06.09
申请号
WO2015US63181
申请日期
2015.12.01
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
发明人
WAGERS, AMY J.;TABEBORDBAR, MOHAMMADSHARIF;CHEW, WEI LEONG;CHURCH, GEORGE M.