| 发明名称 | Antibodies to integrin AVB6 and use of same to treat cancer | ||
| 摘要 | The invention provides antibodies that specifically bind to integrin αvβ6. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting αvβ6. | ||
| 申请公布号 | US9493566(B2) | 申请公布日期 | 2016.11.15 |
| 申请号 | US201314378746 | 申请日期 | 2013.02.14 |
| 申请人 | Seattle Genetics, Inc. | 发明人 | Ryan Maureen;Django Sussman |
| 分类号 | C07K16/00;C07K16/28;C07K16/46;A61K39/395;C07H21/04;A61K47/48;C07K19/00;A61K39/00 | 主分类号 | C07K16/00 |
| 代理机构 | Seattle Genetics, Inc. | 代理人 | Seattle Genetics, Inc. |
| 主权项 | 1. An isolated murine 15H3 monoclonal antibody that specifically binds integrin αvβ6 wherein the antibody comprises a heavy chain variable region comprising the sequence set forth in SEQ ID NO:1 and a light chain variable region comprising the sequence set forth in SEQ ID NO:2; and chimeric or humanized forms thereof. | ||
| 地址 | Bothell WA US | ||