| 发明名称 | Method for preserving aqueous solution containing leuco chromogen | ||
| 摘要 | Described is a method for preserving an aqueous solution comprising a leuco chromogen, comprising adding at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine to the aqueous solution containing a leuco chromogen, and a method for stabilizing a leuco chromogen, comprising allowing the leuco chromogen to coexist in an aqueous solution comprising at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine. | ||
| 申请公布号 | US9493433(B2) | 申请公布日期 | 2016.11.15 |
| 申请号 | US201113811925 | 申请日期 | 2011.08.09 |
| 申请人 | KYOWA MEDEX CO., LTD. | 发明人 | Soya Haruyo;Murakami Tomomi;Tsunoda Haruki;Ohsugi Yu;Yoda Ayako;Matsushita Masashi |
| 分类号 | C09B21/00;C09B67/00;C09B67/42;C07D279/30;C09B67/28;C09B67/44;C12Q1/28;G01N33/72;C09B11/12 | 主分类号 | C09B21/00 |
| 代理机构 | Fitzpatrick, Cella, Harper & Scinto | 代理人 | Fitzpatrick, Cella, Harper & Scinto |
| 主权项 | 1. A method for stabilizing a leuco chromogen, comprising allowing the leuco chromogen to coexist for at least seven days in an aqueous solution comprising at least one compound selected from the group consisting of polyoxyethylene alkylamine with an alkyl having 8 to 20 carbon atoms and polyoxyethylene alkenylamine with an alkenyl having 8 to 20 carbon atoms, wherein the leuco chromogen is a phenothiazine chromogen selected from the group consisting of 10-N-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)-10H-phenothiazine contained at a concentration of 0.0001 to 2.0 mmol/L and 10-N-methylcarbamoyl-3,7-bis(dimethylamino)-10H-phenothiazine contained at a concentration of 0.1 to 2.0 mmol/L in said aqueous solution, and the polyoxyethylene alkylamine or the polyoxyethylene alkenylamine is contained at a concentration of 0.5 to 5% in said aqueous solution. | ||
| 地址 | Tokyo JP | ||