发明名称 IMPROVED DETECTION AND THERAPY OF LESIONS WITH BIOTIN/AVIDIN CONJUGATES
摘要 Uses of compositions in methods for detecting and/or treating targeted lesions in a patient are provided. The compositions used are comprised of a targeting composition comprising a biotin and targeting protein conjugate or an avidin and targeting protein conjugate; optionally, a clearing composition comprised of avidin, when the targeting composition is a biotin conjugate, or biotin, when the targeting composition is an avidin conjugate; a detection or therapeutic composition comprised of a conjugate of avidin or biotin with a targeting protein and detection or therapeutic agent; and, optionally, another detection or therapeutic composition comprised of avidin or biotin conjugated to a detection or therapeutic agent. The compositions, methods of use, and kits for use are also provided.
申请公布号 WO9404702(A2) 申请公布日期 1994.03.03
申请号 WO1993US07754 申请日期 1993.08.20
申请人 IMMUNOMEDICS, INC. 发明人 GOLDENBERG, DAVID, M.
分类号 G01N33/50;A61K31/415;A61K31/70;A61K38/00;A61K39/395;A61K45/00;A61K47/48;A61K49/00;A61K49/16;A61K51/00;A61K51/10;A61P9/00;A61P29/00;A61P31/04;A61P35/00;A61P35/02;C12Q1/00;G01N33/53;G01N33/531;G01N33/532;G01N33/534;G01N33/547;G01N33/563;G01R33/28 主分类号 G01N33/50
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