发明名称 PROCEDIMENTO PER LA PREPARAZIONE DI RIVESTIMENTI DI IDROSSIAPATITE
摘要 Coatings of scarcely crystalline carbonated hydroxyapatite are deposited on metallic or ceramic substrates, by immersing the substrates in a solution containing calcium phosphate and bicarbonate ions, with a molar ratio calcium/phosphate from 0.8 to 2 and a pH from 6.8 to 8.0. Subsequently, the solution is heated to 50-80° C., thus raising the pH and causing a spontaneous deposition of carbonated hydroxyapatite on the substrates. The obtained coatings are highly biocompatible, osteoconductive, bioactive and biodegradable, and can be utilized in structures used for preparing orthopaedic and dental prostheses and implants.
申请公布号 IT1288038(B1) 申请公布日期 1998.09.10
申请号 IT1996PR00021 申请日期 1996.04.30
申请人 FLAMETAL S.P.A.;CHI-BO SRL;3C RESEARCH SRL;BIOTECNIC S.A.;G. CREMASCOLI S.R.L. 发明人 REY CHRISTIAN;RANZ XAVIER
分类号 A61F2/00;A61K6/033;A61L27/32;C04B35/622;C04B41/50;C04B41/85;C23C4/18;C23C22/68 主分类号 A61F2/00
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