The present invention relates to a newly identified receptor belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the receptor. The invention further relates to methods using the receptor polypeptides and polynucleotides as a target for diagnosis and treatment in receptor-mediated disorders. The invention further relates to drug-screening methods using the receptor polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides.
申请公布号
US2008051322(A1)
申请公布日期
2008.02.28
申请号
US20070810360
申请日期
2007.06.05
申请人
MILLENNIUM PHARMACEUTICALS, INC.
发明人
GLUCKSMANN MARIA A.;WEICH NADINE S.;HUNTER JOHN J.;WHITE DAVID;MACBETH KYLE J.;WILLIAMSON MARK J.;MEYERS RACHEL E.;CHUN MIYOUNG