发明名称 |
METHOD AND MEANS FOR PREVENTING AND INHIBITING TYPE III SECRETION IN INFECTIONS CAUSED BY GRAM-NEGATIVE BACTERIA |
摘要 |
<p>A means for decreasing bacterial virulence in a mammal including man or in a plant by inhibition of the Type III secretion system at concentrations that do not prevent or substantially reduce bacterial growth comprises an N-substituted 7-quinolylmethyl amine, in particular one that is further substituted in 5- and 8-position on the quinoline ring. A corresponding therapeutic method and a pharmaceutical composition are also disclosed.</p> |
申请公布号 |
WO2008115118(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
WO2008SE00199 |
申请日期 |
2008.03.18 |
申请人 |
INNATE PHARMACEUTICALS AB;ELOFSSON, MIKAEL |
发明人 |
ELOFSSON, MIKAEL |
分类号 |
A61K31/47;A01N43/00;A01P1/00;A61K31/4709;A61P31/04 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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