发明名称 METHOD OF TREATMENT USING A CYTOKINE ABLE TO BIND IL-18BP TO INHIBIT THE ACTIVITY OF A SECOND CYTOKINE
摘要 The present invention relates to the use of a cytokine-1, preferably from the IL-1 family more preferably IL-1F7b, or an isoform, mutein, fused protein, functional derivative or fragment thereof capable of binding to IL-18BP or a mutein, fused protein, functional derivative or fragment thereof and capable of inhibiting a receptor of a cytokine-2, cytokine-2 being a member of the IL-1 family, preferably IL-18, in the manufacture of a medicament for the treatment or prevention of a disease which is caused or aggravated by inducing said receptor of cytokine-2.
申请公布号 US2009074710(A1) 申请公布日期 2009.03.19
申请号 US20070844617 申请日期 2007.08.24
申请人 ARES TRADING S.A. 发明人 DINARELLO CHARLES A.;KIM SOO-HYUN;BUFLER PHILIP
分类号 A61K38/20;A61K31/7088;A61K38/17;A61K38/19;A61P35/00 主分类号 A61K38/20
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