| 发明名称 | Cell suitable for fermentation of a mixed sugar composition | ||
| 摘要 | The present invention relates to a cell suitable for production of one or more fermentation product from a sugar composition comprising glucose, galactose, arabinose and xylose, wherein the cell comprises two to fifteen copies of one or more xylose isomerase gene or two to fifteen copies of one or more xylose reductase and xylitol dehydrogenase, and two to ten copies of araA, araB and araD, genes, wherein these genes are integrated into the cell genome. | ||
| 申请公布号 | US9499841(B2) | 申请公布日期 | 2016.11.22 |
| 申请号 | US201514750084 | 申请日期 | 2015.06.25 |
| 申请人 | DSM IP ASSETS B.V. | 发明人 | Klaassen Paul;Gielesen Bianca Elisabeth Maria;Van Suylekom Gijsberdina Pieternella;Heijne Wilbert Herman Marie |
| 分类号 | C07K14/395;C12P7/10;C12N1/36;C12N9/02;C12N9/04;C12N9/10;C12N9/12;C12N9/16;C12N9/24;C12N9/26;C12N9/42;C12N9/38;C12N9/50;C12N9/88;C12N9/90;C12N9/92;C12P5/02;C12P7/16;C12P7/18;C12P7/20;C12P7/40;C12P7/42;C12P7/44;C12P7/46;C12P7/48;C12P7/54;C12P7/56;C12P13/00;C12P13/08;C12P13/12;C12P13/20;C12P13/22;C12P17/10;C12P35/00 | 主分类号 | C07K14/395 |
| 代理机构 | McBee Moore Woodward & Vanik IP, LLC | 代理人 | McBee Moore Woodward & Vanik IP, LLC |
| 主权项 | 1. A transformed Saccharomyces cerevisiae cell suitable for producing at least one fermentation product from a sugar composition comprising glucose, galactose, xylose, arabinose and mannose, wherein said cell comprises: (a) two to fifteen copies of at least one xylose isomerase gene or two to fifteen copies of at least one xylose reductase and xylitol dehydrogenase, and (b) from two to ten copies of L-arabinose isomerase (araA), L-ribulokinase (araB), and L-ribulose-5-phosphate 4-epimerase (araD) genes, wherein said genes are integrated into the cell genome, and wherein said cell comprises a disruption or deletion of the GAL80 (transcriptional repressor) gene. | ||
| 地址 | Heerlen NL | ||