| 摘要 |
PURPOSE:To get a medical hardened composition which has high breakdown strength while maintaining low collapse ratio by using an aqueous solution, wherein polyacrylic acid or the like having a specified molecular weight and citric acid or the like are mixed at a specified ratio, as a hardener, and mixing powder, which has tetracalcium phosphate for its main ingredient, into it. CONSTITUTION:Using an aqueous solution, wherein the concentration of the citric acid inside a mixture, or one or more kinds of acids among malic acid, maleic acid, tartaric acid, glycolic acid, or a mixed acid is 20-70wt.%, as a hardener, by mixing a polyacrylic acid of 5000-70000 in molecular weight, or the copolymer of a polyacrylic acid and an itaconic acid having the same or less molecular weight, and citric acid, and citric acid or one or more kinds of acids among malic acid, maleic acid, tartaric acid, and glycolic acid or a mixed acid at the ratio of 0.05-0.1:1, this hardener and powder, which has tetracalcium phosphate for its main ingredient, are mixed. Hereby, the collapse ratio can be reduced without the drop of breakdown strength, and excellent property as a medical hardened composition can be gotten. |
