发明名称 |
Acarbose biosynthesis genes from actinoplanes sp., process for the isolation thereof and the use thereof |
摘要 |
The invention relates to acarbose biosynthesis genes from actinomycetes, predominantly from Actinoplanes sp. SE 50/110 and its mutants, to a process for the isolation of acarbose biosynthesis genes from actinomycetes using a gene probe which has been derived from highly conserved protein regions of known dTDP-glucose dehydratase enzymes for finding the genes acbA (coding for dTDP-glucose synthase), acbB (coding for dTDP-glucose dehydratase) and acbC (coding for a cyclase, in part identical to AroB, bacterial 3-dehydroquinate synthases) or one or more acarbose biosynthesis genes from Actinoplanes sp., and to the use of the acarbose biosynthesis genes./!
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申请公布号 |
US5753501(A) |
申请公布日期 |
1998.05.19 |
申请号 |
US19960606322 |
申请日期 |
1996.02.23 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
CRUEGER, ANNELIESE;PIEPERSBERG, WOLFGANG;DISTLER, JUERGEN;STRATMANN, ANSGAR |
分类号 |
C12N1/21;C07H21/04;C07K14/365;C12N9/88;C12N15/00;C12N15/09;C12N15/11;C12N15/15;C12N15/31;C12N15/52;C12N15/55;C12N15/57;C12N15/60;C12N15/76;C12P19/26;C12P19/28;C12R1/045;(IPC1-7):C12N15/63 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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