发明名称
摘要 PURPOSE:To provide a new artificial polypeptide corresponding to human collagen V type useful as an insulin-supporting carrier. CONSTITUTION:An artificial functional polypeptide represented by formula (X)m-(Y)n-(Z) (X is cell-bound domain peptide of human fibronectin; Y is spacer; Z is polypeptide existing in the sequence and having amino acid sequence represented by formula; (m)and(n)are 1 or 0). Z is a polypeptide obtained by substituting 6th, 9th and 33th Hyp of a polypeptide in human collagen V type alpha1 chain with Pro. Useful as a new polypeptide in the fields where insulin is used.
申请公布号 JP2854445(B2) 申请公布日期 1999.02.03
申请号 JP19910291958 申请日期 1991.10.14
申请人 TAKARA SHUZO KK 发明人 HAJI HIDETAKA;TAKAHARA KAZUHIKO;SATO YOSHIKO;NODA AKIHIRO;KATO IKUNOSHIN;HATAKEI MIKA;YAOI YOSHITO
分类号 A61K8/72;A61K8/64;A61K38/00;A61K38/28;A61P5/00;A61P43/00;A61Q19/08;C07K1/20;C07K14/00;C07K14/47;C07K14/78;C07K19/00;C12N1/21;C12N15/09;C12P21/02;C12R1/19;(IPC1-7):C07K19/00 主分类号 A61K8/72
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