| 摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical capable of being used as an AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid) controlling agent. SOLUTION: A compound is expressed by formula (I) (R<SB>F</SB>is a monofluoro- or polyfluoro-alkyl or a monofluoro- or polyfluoro-cycloalkylalkyl; R<SB>1</SB>is H, an alkylaminocarbonyl or a substituted alkyl; R<SB>2</SB>is H, a halogen, a cycloalkyl or a substituted alkyl; and R<SB>3</SB>to R<SB>6</SB>are identical to or different from one another and are each H, a halogen, a substituted alkyl or a substituted amino). The pharmaceutical contains the compound, an addition salt of the compound with a pharmaceutically acceptable acid or base, or an optical isomer of the compound when it exists. COPYRIGHT: (C)2005,JPO&NCIPI |
