| 发明名称 | Devices and methods for detecting amniotic fluid in vaginal secretions | ||
| 摘要 | The present invention relates to a diagnostic method for the detection of small quantities of amniotic fluid in the vagina. More specifically, the invention relates to the detection of PAMG-1 in the vagina using anti-PAMG-1 antibodies. | ||
| 申请公布号 | US9429580(B2) | 申请公布日期 | 2016.08.30 |
| 申请号 | US201113213735 | 申请日期 | 2011.08.19 |
| 申请人 | N-Dia, Inc. | 发明人 | Fuks Boris;Petrunin Dmitrii Dmitrievich;Zaraisky Evgeny Il'ich;Boltovskaya Marina Nikolayevna;Nazimova Svetlana Vladimirovna;Starosvetskaya Nelly Andronikovna;Konstantinov Alexandr;Marshiskaia Margarita Igorevna |
| 分类号 | G01N33/558;G01N33/68 | 主分类号 | G01N33/558 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A strip device comprising a detector section which is upstream from a capture section and at least two placenta alpha microglobulin-1 (PAMG-1)-specific monoclonal antibodies, wherein one of said monoclonal antibodies is a mobilizable antibody present in the detector section, and the other of said two monoclonal antibodies is immobilized in the capture section, wherein said immobilized antibody has a lower PAMG-1 binding affinity than said mobilizable antibody. | ||
| 地址 | Boston MA US | ||