System and method for eluting and testing substance from exhaled aerosol sample

摘要

A method recovering one or more nonvolatile compounds from an exhaled aerosol collected on an electrostatic filter membrane (205) comprises eluting the nonvolatile compounds from the filter with a polar solvent and collecting the eluate. The method is useful for processing samples collected from a portable breath analysis device comprising a sampling filter membrane for analysis.

主权项

1. A method for recovery of non-volatile compounds from an electrostatic filter membrane, wherein said electrostatic filter membrane is fitted in a housing comprising at least one inlet and at least one outlet and wherein said housing is part of a sampling system for exhaled breath, the method comprising:
providing said electrostatic filter membrane containing an exhaled aerosol comprising a nonvolatile compound; washing said electrostatic filter membrane with a polar organic solvent to form an eluate; collecting said eluate comprising said nonvolatile compound; and pouring said solvent in one of said inlet or outlet and collecting said eluate through the other of said inlet or outlet.