| 发明名称 |
Emulsion containing a non-live medicinal substance |
| 摘要 |
The present invention pertains to an emulsion comprising an aqueous phase and an oily phase, the aqueous phase containing a non-live medicinal substance, wherein the aqueous phase comprises at least 30% w/w sugar. The invention also pertains to a method to shield a medicinal substance present in an aqueous phase emulsified with an oily phase, from interaction with the oily phase, and to a vaccine comprising as an antigen a killed micro-organism or a subunit of a micro-organism, the antigen being present in an aqueous phase that is dispersed in an oily phase, wherein the aqueous phase comprises at least 30% w/w sugar. |
| 申请公布号 |
US9492548(B2) |
申请公布日期 |
2016.11.15 |
| 申请号 |
US201314102575 |
申请日期 |
2013.12.11 |
| 申请人 |
Intervet Inc. |
发明人 |
Mombarg Erwin;Jansen Theodorus;Jagt Henricus Johannes Maria |
| 分类号 |
A61K47/36;A61K38/02;A61K39/17;A61K39/12;A61K39/155;A61K39/215;A61K39/00 |
主分类号 |
A61K47/36 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A vaccine comprising an emulsion comprising an aqueous phase and an oily phase, wherein the aqueous phase contains a non-live medicinal substance, and wherein the aqueous phase comprises at least 30% w/w sugar; wherein the non-live medicinal substance is an inactivated micro-organism or a subunit of a micro-organism; wherein the vaccine has a titer; and wherein the titer of the vaccine remains at the same level for at least 17 months of storage at 2-8° C. |
| 地址 |
Madison NJ US |
