Compounds

摘要

The present invention relates to compounds of formula (I):;
wherein R1 and R2 are as defined herein. In certain embodiments, the compounds of the present invention are inhibitors of RORγt and are useful in the treatment of diseases and conditions mediated by RORγt.

主权项

1. A pharmaceutical composition comprising a pharmaceutically or veterinarily acceptable excipient and a compound of formula (I):wherein:
R1 is selected from the group consisting of H, F and OH; R2 is selected from the group consisting of C1-3 alkyl, C1-3 haloalkyl and cyclopropyl;
provided that, when R1 is H, R2 is C1-3 haloalkyl; or a pharmaceutically or veterinarily acceptable salt, solvate or hydrate thereof, a deuterated or tritiated derivative thereof, or a stereoisomer thereof;wherein the pharmaceutical composition is orally bioavailable.