发明名称 |
5-OXOPROLINASE |
摘要 |
The present invention is directed to isolated nucleic acid molecules encoding mammalian 5-oxoprolinase (m 5-OPase). Expression vectors and host cells comprising the nucleic acid molecules are also provided, as well as methods for increasing or decreasing the expression of m 5-OPase in host cells. The invention further provides a method of screening a substance for the ability of the substance to modify m 5-OPase function, and a method for isolating other m 5-OPase molecules. DNA oligomers and antibodies specific for m 5-OPase are provided, each of which can be used to detect m 5-OPase in a sample.
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申请公布号 |
WO9825945(A1) |
申请公布日期 |
1998.06.18 |
申请号 |
WO1997US22851 |
申请日期 |
1997.12.04 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
YE, GUI-JIE;BRESLOW, ESTHER;MEISTER, ALTON +DI |
分类号 |
C12N9/86;(IPC1-7):C07H21/02;C07H21/04;C12N5/00;C12N5/06;C12N15/00;C12P21/00;C12Q1/68 |
主分类号 |
C12N9/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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