发明名称 |
Production of viruses, viral isolates and vaccines |
摘要 |
The present invention discloses methods for producing and/or propagating virus particles, such as influenza virus particles, that are present in a virus isolate obtained from an infected subject by contacting a host cell with a virus particle and culturing the cell under conditions conducive to propagation of the virus particle. The invention also provides a method for selective propagation of a set of virus particles, such as influenza virus particles present in an influenza isolate, which have an affinity for receptors comprising a specific glycosylation residue.
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申请公布号 |
US2008050403(A1) |
申请公布日期 |
2008.02.28 |
申请号 |
US20070879422 |
申请日期 |
2007.07.16 |
申请人 |
CRUCELL HOLLAND B.V. |
发明人 |
MARZIO GIUSEPPE;PAU MARIA G.;OPSTELTEN DIRK J.E.;UYTDEHAAG ALPHONSUS GERARDUS C.M. |
分类号 |
C12N7/01;A61K39/13;A61K39/155;A61K39/235;A61P37/04;C07K14/11;C12N7/00;C12N15/00 |
主分类号 |
C12N7/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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