| 摘要 |
PROBLEM TO BE SOLVED: To provide prognostic methods which are useful in medicine, particularly cancer chemotherapy, particularly, a method for assessing GST-pi expression levels in fixed or fixed and paraffin embedded tissues and prognosticate the probable resistance or sensitivity of a patient's tumor to treatment with platinum-based therapies. SOLUTION: The prognostic method includes examining the amount of GST-pi mRNA in patient's tumor cells and comparing it to a predetermined threshold expression level. More specifically, the invention provides oligonucleotide primer pair GST-piand methods comprising their use for detection of levels of GST-pi mRNA of a pair of oligonucleotide primer. COPYRIGHT: (C)2009,JPO&INPIT
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