| 发明名称 |
СПОСОБ ПОЛУЧЕНИЯ ФТОРОРГАНИЧЕСКИХ СОЕДИНЕНИЙ В СПИРТОВЫХ РАСТВОРИТЕЛЯХ |
| 摘要 |
The present invention relates to a method for preparation of organofluoro compounds containing radioactive isotope fluorine-18. More particularly, the present invention relates to a method for preparation of organofluoro compound [18F]florbetaben or [18F]AV-45 having <Chemistry Formula 11> and <Chemistry Formula 12>, respectively, by reacting fluorine salt containing radioactive isotope fluorine-18 with alkyl halide or alkyl sulfonate in the presence of alcohol of Chemistry Formula 1 as a solvent to obtain high yield of organofluoro compound. Synthesis reaction according to the present invention may be carried out under mild condition to give high yield of the organofluoro compounds and the reaction time is decreased, and thereby is suitable for the mass production of the organofluoro compounds. |
| 申请公布号 |
RU2007126814(A) |
申请公布日期 |
2009.01.27 |
| 申请号 |
RU20070126814 |
申请日期 |
2005.12.09 |
| 申请人 |
ФЬЮЧЕРКЕМ КО., ЛТД. (KR);ДЗЕ ЭЙШН ФАУНДЕЙШН (KR) |
发明人 |
МООН Дае Хиук (KR);ТИ Дае Йоон (KR);КИМ Донг Воок (KR);ОХ Сеунг Дзун (KR);РИУ Дзин-соок (KR) |
| 分类号 |
C07C17/007 |
主分类号 |
C07C17/007 |
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