发明名称 КОМБИНАЦИИ ТЕРАПЕВТИЧЕСКИХ АГЕНТОВ ДЛЯ ЛЕЧЕНИЯ РАКА
摘要 A combination therapy for treating patients suffering from proliferative diseases or diseases associated with persistent angiogenesis is disclosed. The patient is treated with a camptothecin derivative and one or more chemotherapeutic agents selected from a microtubule active agent; an alkylating agent; an anti-neoplastic anti-metabolite; a platin compound; a topoisomerase II inhibitor; a VEGF inhibitor; a tyrosine kinase inhibitor; an EGFR kinase inhibitor; an mTOR kinase inhibitor; an insulin-like growth factor I inhibitor; a Raf kinase inhibitor; a monoclonal antibody; a proteasome inhibitor; a HDAC inhibitor; and ionizing radiation.
申请公布号 RU2007126978(A) 申请公布日期 2009.01.27
申请号 RU20070126978 申请日期 2005.12.13
申请人 НОВАРТИС АГ (CH);СИГМА-ТАУ ИНДУСТРИЕ ФАРМАСЕУТИКЕ РЮНИТЕ С.П.А. (IT) 发明人 ЗАКНОЕН Сара (US);ВУ Маргарет Мей (US);ВЕРСЕЙС Ричард Уилль м (US);ПИСАНО Клаудио (IT);ВЕШ Лореданна (IT)
分类号 A61K31/4745 主分类号 A61K31/4745
代理机构 代理人
主权项
地址