发明名称 |
КОМБИНАЦИИ ТЕРАПЕВТИЧЕСКИХ АГЕНТОВ ДЛЯ ЛЕЧЕНИЯ РАКА |
摘要 |
A combination therapy for treating patients suffering from proliferative diseases or diseases associated with persistent angiogenesis is disclosed. The patient is treated with a camptothecin derivative and one or more chemotherapeutic agents selected from a microtubule active agent; an alkylating agent; an anti-neoplastic anti-metabolite; a platin compound; a topoisomerase II inhibitor; a VEGF inhibitor; a tyrosine kinase inhibitor; an EGFR kinase inhibitor; an mTOR kinase inhibitor; an insulin-like growth factor I inhibitor; a Raf kinase inhibitor; a monoclonal antibody; a proteasome inhibitor; a HDAC inhibitor; and ionizing radiation. |
申请公布号 |
RU2007126978(A) |
申请公布日期 |
2009.01.27 |
申请号 |
RU20070126978 |
申请日期 |
2005.12.13 |
申请人 |
НОВАРТИС АГ (CH);СИГМА-ТАУ ИНДУСТРИЕ ФАРМАСЕУТИКЕ РЮНИТЕ С.П.А. (IT) |
发明人 |
ЗАКНОЕН Сара (US);ВУ Маргарет Мей (US);ВЕРСЕЙС Ричард Уилль м (US);ПИСАНО Клаудио (IT);ВЕШ Лореданна (IT) |
分类号 |
A61K31/4745 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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