发明名称 METHOD FOR INSPECTING SCOLIOSIS BASED ON SINGLE NUCLEOTIDE POLYMORPHISM IN NO.9 CHROMOSOME SHORT ARM 22.2 REGION
摘要 PROBLEM TO BE SOLVED: To provide a method for inspecting scoliosis, and a method for screening a medicine for preventing or treating scoliosis.SOLUTION: A single nucleotide polymorphism that exists in a No.9 chromosome short arm 22.2 region (9p22.2 region) is analyzed, and onset risk and/or presence of onset of scoliosis is inspected based on the analysis result. Further, an mRNA of a BNC2 gene of an expression level of protein is measured, and scoliosis is inspected based on the measurement result. Further, screening of a medicine for preventing or treating scoliosis is performed by selecting a substance which changes the expression level of the BNC2 gene.SELECTED DRAWING: Figure 1
申请公布号 JP2016214091(A) 申请公布日期 2016.12.22
申请号 JP20150099417 申请日期 2015.05.14
申请人 INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH 发明人 IKEGAWA SHIRO
分类号 C12Q1/68;C12N15/00;C12N15/09;G01N33/53 主分类号 C12Q1/68
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