Method of manufacturing liposomes

摘要

The present invention relates to a method of making a liposome, said method comprising the steps of: (a) mixing a lipophilic phase and a hydrophilic phase, said lipophilic phase comprising an amphiphilic bilayer-forming substance; and (b) applying a cavitational sheer force to said mixture to form said liposome; wherein said cavitational force is created by contacting said mixture with a member that vibrates at an ultrasonic frequency.